Selvakumar Edwardraja PhD


Specialization

Protein Design & Engineering / Bioinformatics

 

Education

Sep/2006-Jun/2010
Ph.D. in Chemical Engineering, BK-21 Fellowship
Biomolecular Engineering Lab, Pusan National University, KR

Advisor: Prof. Sun-Gu Lee
Title: "Engineering of Antibody Variable Domains Based on Stable Human Frameworks" (Abstract)

July/2002-Jun/2003
Advanced Post Graduate Diploma in Bioinformatics
Centre of Excellence in Bioinformatics, Pondicherry University, IN

Advisors: Prof. PP Mathur and SL Hoti
Vector Control Research Centre, Pondicherry University, IN
Title: "Comparative Genomics of Infective Parasite and Free-living Nematode For Drug/Vaccine Target Identification"

2000-2002
Master of Science in Botany (Splz. in Microbiology)
The American College, Madurai Kamaraj Univerisity, IN

Advisor: Dr. D. Stephen
Title: "ARBORATICS – Model Software Development For Identification, Location And Documentation Of Higher Plants For Internet"

1997-2000
Bachelor of Science in Industrial Microbiology
Thiagarajar College, Madurai Kamaraj Univerisity, IN

Advisor: Dr. P. Suresh
Title: "Studies On Certain Cultivation Aspects Of Milky Mushroom (Calocybe indica P&C)"

 

Appointments

Aug/2016-Present
Research Officer (Protein Engineering)
Institute for Molecular Biosciences, University of Queensland, Australia

Feb/2016-June/2016
Postdoctoral Researcher (Bioinformatics)
Inst. of Env. Tech. and Industry, Pusan National University, Korea (Republic of)

Sep/2012-March/2015
EMBO-Postdoctoral Fellow (Protein Engineering)
Dept. of Biol. Chem., Technical University of Munich, Germany

Oct/2011-May/2012
Postdoctoral Associate (Protein Engineering)
Dept. of Chem & Biochemistry, Arizona State University, USA

Sep/2010-Aug/2011
Postdoctoral Associate (Synthetic Biology)
Dept. of Chemistry, University at Buffalo, USA

Nov/2004-Aug/2006
Computer Operator (Bioinformatics)
Centre of Excellence in Bioinformatics, Pondicherry University, IN

May/2004-Nov/2004
Research Studentship (Bioinformatics)
 Centre of Excellence in Bioinformatics, Pondicherry University, IN

Dec/2003-Apr/2004
Adjunct Faculty (Bioinformatics)
 Centre of Excellence in Bioinformatics, Pondicherry University, IN

 Courses taught: Bioinformatics-I, Bioinformatics-II, Lab-1, Lab-2

 

Research Proficiencies

Specialized
Designing Chimeric Proteins, Active Site Grafting, Antibody Variable Domain Engineering, Unnatural Amino Acid Incorporation (Site specific / Global)

Genome stuffs
ORF prediction, Operon structure, Promoter identification, Regulator Binding sites, Motif analysis (Regular Expressions),  Repeat sequences, GC content, Metabolic pathway mapping

DNA stuffs
Genome & Gene sequence analysis, Gene/homologous Finding, Motif analysis, Gene Designing for optimal expression, Codon optimization, mRNA 2ndry structure analysis, PCRs (Assembly -Gene synthesis / Overlap - Gene Fusion), Site Directed Mutagenesis, Saturation Mutagenesis, Directed Evolution

Protein stuffs
Protein Designing, Consensus Engineering, Phylogenetic analysis, Over-expression, extraction and Column Purifications (Native/Denatured), SDS-PAGE, Western Blot, Quantification

Characterization
LC-ESI-MS, ELISA, CD Spec, Homology Modelling, Structure Analysis, Active site engineering, Protein-Substrate docking, Molecular Dynamics Simulations, Protein-Protein interaction analysis (sequence / structural context), Motif based Functional Annotations

Computational
Linux System Administration (Unix, Linux, Irix), Network Engineering, Web Designing & Administration (LAMP), Apache, Bash Shell scripts, C/C++, Perl & CGI script, MySQL, Beowulf-Clustering

 

Publications

From PubMed  or  Publication Page

 

Research Fellowships

2006-2010
PhD Graduate Fellowship
Brain Korea-21, Govt. of Korea

2003 (6 months)
Research Studentship
Dept. of Biotechnology, Govt. of India

2002-2003
Adv. PG. Dip. Fellowship
Dept. of Biotechnology, Govt. of India

2001-2002
Students Project Scheme
TN State Council for Science & Technology, Govt. of India

 

Awards & Recognitions

Dec/2009
Runner-up: Student Poster Scholarship Program
Antibody Engineering & Antibody Therapeutics,
San Diego, CA, USA

Nov/2009
Best Oral Presentation
2009 KSBB Meeting and International Symposium
Daejeon, Korea

Oct/2008
Best Poster Presentation
2008 KSBB Meeting and International Symposium
 Jeju, Korea

 

Trainings / Workshops

2006
Accelrys Discovery Studio Software Training
University of Pune, Pune

2005
Machine Learning Techniques in Functional Proteomics
Institute of Microbial Technology, Chandigarh

2005
Basic Techs. in Mol Biol, Bioinfor & Pharmacogenomics
Jawaharlal Inst. of PG Med. Edu. and Res (JIPMER), Pondicherry

2004
Workshop on Molecular Modelling
Anna University, Chennai

2003
South East Asian Training Course on Bioinformatics
Intl. Centre for Genetic Engg. & Biotechnol, New Delhi

 

Professional Affiliations

-NIL-

 

References

References available upon request.